Seasonal Influenza in Kosovo: An Epidemiological Analysis in the Municipality of Gjilan for the Period September–December at the Family Medicine Center “Nagip Rexhepi”

Authors

  • Flutura Rexhepi Medicinale

DOI:

https://doi.org/10.5281/zenodo.18519085

Keywords:

seasonal influenza, influenza-like illness, epidemiology, primary healthcare, Kosovo, Gjilan, family medicine, outpatient care

Abstract

Seasonal influenza is a common acute respiratory infection with a substantial impact on primary healthcare services worldwide. This study provides an epidemiological analysis of seasonal influenza in the Municipality of Gjilan, Kosovo, using routinely collected data from the Family Medicine Center “Nagip Rexhepi” for the period September–December 2023. A retrospective descriptive design was applied to the records of 240 patients diagnosed with seasonal influenza. Demographic variables, clinical manifestations, comorbidities, and temporal distribution were analyzed. The mean age of patients was distributed across all age groups, with 25.0% aged 0–14 years, 45.8% aged 15–49 years, 16.7% aged 50–64 years, and 12.5% aged 65 years or older. Females accounted for 54.2% of cases. The highest number of cases occurred in November (37.5%) and December (29.2%), confirming a clear seasonal peak in late autumn and early winter. The most frequent symptoms were fever (91.7%), cough (87.5%), sore throat (75.0%), fatigue (79.2%), myalgia (70.8%), and headache (66.7%). Comorbidities included hypertension (16.7%), diabetes (12.5%), chronic respiratory disease (10.4%), and cardiac disease (8.3%). Twelve patients (5.0%) were referred to secondary care, and eight cases (3.3%) were classified as severe. The findings highlight the important role of primary healthcare in the early detection, management, and surveillance of influenza and provide evidence to inform local prevention and vaccination strategies.

References

Ministry of Health of the Republic of Kosovo. (2023). Raporti vjetor i survejancës së gripit sezonal 2022–2023. Instituti Kombëtar i Shëndetit Publik të Kosovës (IKSHPK). https://www.ikshpk.rks-gov.net

National Institute of Public Health of Kosovo. (2022). Influenza weekly bulletin: Surveillance report for Kosovo. IKSHPK. https://www.niph-rks.org

National Institute of Public Health of Kosovo. (2021). Epidemiological bulletin of influenza-like illness (ILI) and severe acute respiratory infections (SARI). IKSHPK. https://www.niph-rks.org

Institute of Public Health of Albania. (2022). Raporti vjetor i gripit sezonal në Shqipëri 2021–2022. ISHP. https://www.ishp.gov.al

Institute of Public Health of North Macedonia. (2023). Seasonal influenza report 2022–2023. IPH Skopje. http://iph.mk

Public Health Institute of Montenegro. (2022). Annual influenza surveillance report. Institute of Public Health of Montenegro. https://www.ijzcg.me

Croatian Institute of Public Health. (2022). Seasonal influenza epidemiological report for Croatia. Hrvatski zavod za javno zdravstvo. https://www.hzjz.hr

Serbian Institute of Public Health “Dr. Milan Jovanović Batut”. (2023). Influenza surveillance and weekly reports. https://www.batut.org.rs

Dora, C., et al. (2020). Epidemiological characteristics of influenza-like illness in the Western Balkans region. Balkan Journal of Public Health, 7(2), 45–53. https://doi.org/10.14712/bjph.2020.235

Hoxha, R., & Krasniqi, B. (2019). Seasonal influenza patterns in Kosovo: An analysis of surveillance data from primary healthcare centers. Albanian Medical Journal, 3(19), 85–94.

Gashi, M., & Berisha, M. (2021). Trends of influenza-like illness in Kosovo during winter seasons 2015–2020. International Journal of Infectious Diseases, 103, 234–240. https://doi.org/10.1016/j.ijid.2020.12.144

Berisha, M., Pllana, M., & Gashi, B. (2018). Influenza surveillance and virological confirmations in Kosovo: A five-year review. Kosovo Journal of Medical Sciences, 4(1), 12–20.

Kosovo Agency of Statistics. (2023). Health statistics report: Respiratory infections and influenza cases. KAS. https://ask.rks-gov.net

World Health Organization. (2023). Influenza (Seasonal). WHO. https://www.who.int/news-room/fact-sheets/detail/influenza-(seasonal)

World Health Organization. (2022). Global influenza strategy 2019–2030. WHO. https://www.who.int/publications/i/item/9789241515320

Centers for Disease Control and Prevention. (2023). Influenza symptoms & complications. CDC. https://www.cdc.gov/flu/symptoms/symptoms.htm

Centers for Disease Control and Prevention. (2022). Overview of influenza surveillance in the United States. CDC. https://www.cdc.gov/flu/weekly/overview.htm

Paget, J., Spreeuwenberg, P., Charu, V., Taylor, R. J., Iuliano, A. D., Bresee, J., Simonsen, L., & Viboud, C. (2019). Global mortality associated with seasonal influenza epidemics: New burden estimates and predictors from the GLaMOR project. Journal of Global Health, 9(2), 020421. https://doi.org/10.7189/jogh.09.020421

Iuliano, A. D., Roguski, K. M., Chang, H. H., Muscatello, D. J., Palekar, R., Tempia, S., Cohen, C., Schanzer, D., Cowling, B. J., Wu, P., & others. (2018). Estimates of global seasonal influenza–associated respiratory mortality: A modelling study. The Lancet, 391(10127), 1285–1300. https://doi.org/10.1016/S0140-6736(17)33293-2

Caini, S., Kroneman, M., Wiegers, T., El Guerche-Séblain, C., & Paget, J. (2018). Clinical characteristics and severity of influenza infections: Results of the global Influenza Hospital Surveillance Network. PLOS ONE, 13(3), e0194516. https://doi.org/10.1371/journal.pone.0194516

Monto, A. S., & Fukuda, K. (2020). Epidemiology of seasonal influenza. Vaccine, 38(6), 1014–1021. https://doi.org/10.1016/j.vaccine.2019.10.070

Krammer, F., Smith, G. J., Fouchier, R. A., Peiris, M., Kedzierska, K., Doherty, P. C., Palese, P., Shaw, M. L., Treanor, J., Webster, R. G., & others. (2018). Influenza. Nature Reviews Disease Primers, 4(1), 3. https://doi.org/10.1038/s41572-018-0002-y

Wong, K. C., Luscombe, G. M., & Hawke, C. (2019). Influenza infections in primary care: A comparison of sentinel and general practice surveillance data in Australia. BMC Infectious Diseases, 19(1), 941. https://doi.org/10.1186/s12879-019-4591-2

Dawood, F. S., Hunt, D. R., Patel, M., De León, R. O., Komatsu, K. K., Tran, T., D’Mello, T., & others. (2020). Incidence of influenza in outpatient settings: A systematic review. Clinical Infectious Diseases, 70(1), 1–9. https://doi.org/10.1093/cid/ciz164

European Centre for Disease Prevention and Control. (2023). Seasonal influenza – Factsheet. ECDC. https://www.ecdc.europa.eu/en/seasonal-influenza

Jain, S., Kamimoto, L., Bramley, A. M., Schmitz, A. M., Benoit, S. R., Louie, J., Sugerman, D. E., Druckenmiller, J. K., Ritger, K., Chugh, R., & others. (2011). Hospitalized patients with influenza A(H1N1)pdm09 virus infection—United States, April–June 2009. New England Journal of Medicine, 362(27), 2375–2385. https://doi.org/10.1056/NEJMoa1000573

Rolfes, M. A., Foppa, I. M., Garg, S., Flannery, B., Brammer, L., Singleton, J., Burns, E., Jernigan, D. B., & Bresee, J. S. (2018). Annual estimates of the burden of seasonal influenza in the United States. Influenza and Other Respiratory Viruses, 12(1), 132–137. https://doi.org/10.1111/irv.12486

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Published

2025-01-30

How to Cite

Rexhepi, F. (2025). Seasonal Influenza in Kosovo: An Epidemiological Analysis in the Municipality of Gjilan for the Period September–December at the Family Medicine Center “Nagip Rexhepi”. Ege Scholar Journal, 2(1), 35–43. https://doi.org/10.5281/zenodo.18519085

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Section

Research Articles